Annual report pursuant to Section 13 and 15(d)

Stockholders??? Equity (Details Narrative)

v3.23.1
Stockholders’ Equity (Details Narrative) - USD ($)
1 Months Ended 3 Months Ended 12 Months Ended
Feb. 14, 2023
Feb. 03, 2023
Apr. 01, 2022
Mar. 29, 2022
Mar. 23, 2022
Aug. 20, 2021
Jun. 16, 2021
Jun. 08, 2021
Feb. 24, 2021
Oct. 06, 2020
Jan. 31, 2023
Mar. 25, 2023
Dec. 31, 2022
Dec. 31, 2021
Jan. 01, 2022
Class of Stock [Line Items]                              
Common stock, shares authorized                         50,000,000 30,000,000 50,000,000
Preferred stock, shares issued                         0 0  
Preferred stock, shares outstanding                         0 0  
Proceeds from issuance of stock                         $ 6,400,000    
Shares issued in private placement, net of transaction costs, value                           $ 9,875,550  
Repurchase of common stock value                         $ 300,000    
Restricted Stock Units (RSUs) [Member]                              
Class of Stock [Line Items]                              
Number of shares, forfeited                         68,539 4,000  
Number of shares, granted     1,979,818                   2,428,285 457,593  
Restricted Stock Units (RSUs) [Member] | Federal, State and Local [Member]                              
Class of Stock [Line Items]                              
Number of shares, forfeited                         36,145    
Restricted Stock [Member]                              
Class of Stock [Line Items]                              
Number of shares, forfeited                         33,489 10,706  
Number of shares, granted                         187,058 37,500  
Restricted Stock [Member] | Employment Termination [Member]                              
Class of Stock [Line Items]                              
Number of shares, forfeited                           1,530  
Restricted Stock [Member] | Federal, State and Local [Member]                              
Class of Stock [Line Items]                              
Number of shares, forfeited                           9,176  
Common Stock [Member]                              
Class of Stock [Line Items]                              
Shares issued during period                           1,321,132  
Shares issued in connection with the Purchase Agreement with Lincoln Park                         123,609    
Shares issued in connection with license agreement                         100,000 144,689  
Shares issued in private placement, net of transaction costs, value                           $ 132  
Repurchase of common stock value                            
Common Stock [Member] | Restricted Stock Units (RSUs) [Member]                              
Class of Stock [Line Items]                              
Shares issued during period                           14,300  
Number of shares, granted                           17,800  
Director [Member] | Restricted Stock [Member]                              
Class of Stock [Line Items]                              
Number of shares, forfeited                         18,208    
Employees [Member] | Restricted Stock [Member]                              
Class of Stock [Line Items]                              
Number of shares, granted               37,500              
Consultants [Member]                              
Class of Stock [Line Items]                              
Options and warrants granted                           180,000  
Consultants [Member] | Restricted Stock [Member]                              
Class of Stock [Line Items]                              
Number of shares, granted                         59,766    
Consultants [Member] | Common Stock [Member]                              
Class of Stock [Line Items]                              
Number of shares, granted                           17,800  
Aposense, Ltd. [Member]                              
Class of Stock [Line Items]                              
Number of repurchase of common stock, shares       100,000                      
Repurchase of common stock value       $ 300,000                      
Purchase Agreement [Member] | Lincoln Park Capital Fund LLC [Member]                              
Class of Stock [Line Items]                              
Shares issued in connection with the Purchase Agreement with Lincoln Park         123,609               123,609    
Number of common stock issued on commitment fees, value         $ 450,000                    
Reimbursement fees         25,000                    
Purchase Agreement [Member] | Lincoln Park Capital Fund LLC [Member] | Maximum [Member]                              
Class of Stock [Line Items]                              
Commitment to purchase common stock         $ 15,000,000.0                    
Number of common stock shares in regular purchase         25,000                    
Number of common stock shares exceeding regular purchase         75,000                    
Daily maximum committed purchase obligations, value         $ 1,250,000                    
Maximum number of shares sold         3,142,430                    
Nasdaq's exchange cap percent         19.99%                    
Beneficial ownership limitation percentage         9.99%                    
Purchase Agreement [Member] | Lincoln Park Capital Fund LLC [Member] | Minimum [Member]                              
Class of Stock [Line Items]                              
Minimum closing sale price         $ 1.00                    
Sales Agreement [Member]                              
Class of Stock [Line Items]                              
Proceeds from issuance of stock                           $ 174,000  
Shares issued during period                           21,597  
Price per share                           $ 8.33  
Sales Agreement [Member] | Maximum [Member]                              
Class of Stock [Line Items]                              
Maximum number of shares to be sold at the market offering           $ 30,000,000.0                  
License Agreement [Member] | Elion Oncology [Member]                              
Class of Stock [Line Items]                              
Shares issued in connection with license agreement                   825,000     100,000 100,000  
License Agreement [Member] | Ocuphire Pharma Inc [Member]                              
Class of Stock [Line Items]                              
Shares issued in connection with license agreement             44,689                
License Agreement [Member] | Aposense, Ltd. [Member]                              
Class of Stock [Line Items]                              
Shares issued in connection with license agreement                   625,000          
Private Placement [Member]                              
Class of Stock [Line Items]                              
Shares issued during period                 1,321,132            
Gross proceeds from issuance of common stock                 $ 10,200,000            
Shares issued in private placement, net of transaction costs, value                 $ 9,900,000            
Private Placement [Member] | Placement Agent [Member]                              
Class of Stock [Line Items]                              
Warrants issued to purchase common stock                 79,268            
Warrants exercise price                 $ 9.30            
Warrant expiration date                 Feb. 16, 2023            
Subsequent Event [Member]                              
Class of Stock [Line Items]                              
Proceeds from issuance of stock                       $ 7,000,000.0      
Shares issued during period                       8,432,192      
Subsequent Event [Member] | Purchase Agreement [Member] | Lincoln Park Capital Fund LLC [Member]                              
Class of Stock [Line Items]                              
Proceeds from issuance of stock                     $ 54,000        
Shares issued during period                     50,000        
Price per share                     $ 1.08        
Subsequent Event [Member] | Sales Agreement [Member] | Oppenheimer & Co. Inc, [Member]                              
Class of Stock [Line Items]                              
Proceeds from issuance of stock   $ 693,000                          
Shares issued during period   569,648                          
Price per share   $ 1.22                          
Subsequent Event [Member] | Sales Agreement [Member] | Oppenheimer & Co. Inc, [Member] | Maximum [Member]                              
Class of Stock [Line Items]                              
Maximum number of shares to be sold at the market offering   $ 30,000,000.0                          
Subsequent Event [Member] | Securities Purchase Agreement [Member] | Registered Direct Offering [Member] | Accredited Investor [Member]                              
Class of Stock [Line Items]                              
Proceeds from issuance of stock $ 5,700,000                            
Shares issued during period 7,812,544                            
Price per share $ 0.80                            
Gross proceeds from issuance of common stock $ 6,300,000                            
Subsequent Event [Member] | Securities Purchase Agreement [Member] | Registered Direct Offering [Member] | Accredited Investor [Member] | Common Stock [Member]                              
Class of Stock [Line Items]                              
Gross proceeds from issuance of common stock $ 6,300,000